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Streptomycin is the first-in-class aminoglycoside antibiotic . It is derived from Streptomyces griseus and is the earliest modern agent used against tuberculosis . Streptomycin lacks the common 2-deoxystreptamine moiety (image right, below) present in most other members of this class. Other examples of aminoglycosides include the deoxystreptamine-containing agents kanamycin , tobramycin , gentamicin , and neomycin (see below).